Manufacturer: YUSHISEIHIN Co.,Ltd.
Product: PEGylation Agents

Description

NOF Corporation offers high-quality polyethylene glycol (PEG) modifiers, including the SUNBRIGHT® and PUREBRIGHT® series, designed for bioactive substance preparation such as pharmaceuticals and proteins. These PEGs, with exceptional purity and diverse functional groups, serve as optimal bases for drug delivery system (DDS) applications. Functional group variations allow PEG chains to integrate into drugs, enzymes, phospholipids, and other biological substances.

By combining hydrophobic polymers with PEG modifiers, polymer micelles can form, enabling stable dispersion of hydrophobic drugs in water. Monodisperse PEGs, increasingly used as linkers for antibody-drug conjugates (ADCs), enhance hydrophilicity. PEG modification stabilizes drugs, reduces antigenicity and dosage, and improves targeting by attaching antibodies to the surface.